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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDS5B
All Species:
10.61
Human Site:
S1315
Identified Species:
19.44
UniProt:
Q9NTI5
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NTI5
NP_055847.1
1447
164667
S1315
M
K
T
S
K
K
G
S
K
K
K
S
G
P
P
Chimpanzee
Pan troglodytes
XP_509623
1487
169149
S1355
M
K
T
S
K
K
G
S
K
K
K
S
G
P
P
Rhesus Macaque
Macaca mulatta
XP_001118201
1528
173307
S1395
L
K
T
S
K
K
G
S
K
K
K
S
G
L
P
Dog
Lupus familis
XP_543139
1623
183240
K1491
K
T
S
K
K
G
A
K
K
K
S
G
P
S
A
Cat
Felis silvestris
Mouse
Mus musculus
Q4VA53
1446
164401
N1313
M
K
T
S
K
K
G
N
K
K
K
L
V
P
P
Rat
Rattus norvegicus
Q6TRW4
1447
164441
N1314
V
K
T
S
K
K
G
N
K
K
K
P
A
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509617
1452
165101
G1318
R
G
S
R
K
R
S
G
P
P
A
A
A
A
G
Chicken
Gallus gallus
Q5F3U9
1412
161007
E1278
D
V
I
E
S
E
D
E
Q
N
S
P
P
K
K
Frog
Xenopus laevis
Q5U241
1464
166906
V1318
P
K
R
G
R
K
N
V
V
P
I
E
S
P
P
Zebra Danio
Brachydanio rerio
A1L1F4
1320
148940
G1189
R
D
V
S
S
E
V
G
A
R
E
N
E
E
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610719
1218
138870
K1087
E
F
S
L
G
S
D
K
R
D
N
Y
K
M
W
Honey Bee
Apis mellifera
XP_623860
1203
137941
W1072
N
N
M
N
Y
K
L
W
A
V
C
D
L
A
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790621
1624
181368
T1388
P
K
S
A
T
P
T
T
T
T
R
G
R
P
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.1
94.3
88.4
N.A.
96.3
96.4
N.A.
94.4
91.4
84.4
63.9
N.A.
27.9
33.6
N.A.
40.3
Protein Similarity:
100
97.1
94.5
88.8
N.A.
97.7
97.7
N.A.
96.6
94.6
90.4
75.4
N.A.
46.5
52.3
N.A.
58.8
P-Site Identity:
100
100
86.6
20
N.A.
80
73.3
N.A.
6.6
0
26.6
6.6
N.A.
0
6.6
N.A.
13.3
P-Site Similarity:
100
100
93.3
26.6
N.A.
86.6
86.6
N.A.
26.6
13.3
33.3
33.3
N.A.
13.3
13.3
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
8
0
16
0
8
8
16
16
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
8
8
0
0
0
0
16
0
0
8
0
8
0
0
0
% D
% Glu:
8
0
0
8
0
16
0
8
0
0
8
8
8
8
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
8
8
8
39
16
0
0
0
16
24
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% I
% Lys:
8
54
0
8
54
54
0
16
47
47
39
0
8
8
8
% K
% Leu:
8
0
0
8
0
0
8
0
0
0
0
8
8
8
0
% L
% Met:
24
0
8
0
0
0
0
0
0
0
0
0
0
8
8
% M
% Asn:
8
8
0
8
0
0
8
16
0
8
8
8
0
0
8
% N
% Pro:
16
0
0
0
0
8
0
0
8
16
0
16
16
47
47
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
16
0
8
8
8
8
0
0
8
8
8
0
8
0
0
% R
% Ser:
0
0
31
47
16
8
8
24
0
0
16
24
8
8
0
% S
% Thr:
0
8
39
0
8
0
8
8
8
8
0
0
0
0
8
% T
% Val:
8
8
8
0
0
0
8
8
8
8
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _